Cell engraftment, vascularization, and inflammation after treatment of equine distal limb wounds with endothelial colony forming cells encapsulated within hydrogel microspheres

Cell engraftment, vascularization, and inflammation after treatment of equine distal limb wounds with endothelial colony forming cells encapsulated within hydrogel microspheres

Abstract Background Endothelial colony forming cells (ECFCs) may be useful therapeutically in conditions with poor blood supply, such as distal limb wounds in the horse. Encapsulation of ECFCs into injectable hydrogel microspheres may ensure cell survival and cell localization to improve neovascular...

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Bibliographic Details
Main Authors: Randolph L. Winter, Yuan Tian, Fred J. Caldwell, Wen J. Seeto, Jey W. Koehler, David A. Pascoe, Shirley Fan, Phillippe Gaillard, Elizabeth A. Lipke, Anne A. Wooldridge
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Veterinary Research
Subjects:
Equine
Endothelial colony forming cells
Stem cell therapy
Regenerative medicine
Biomaterial
Microsphere
Online Access:https://doi.org/10.1186/s12917-020-2269-y

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