Exposure via biotransformation: Oxazepam reaches predicted pharmacological effect levels in European perch after exposure to temazepam

It is generally expected that biotransformation and excretion of pharmaceuticals occurs similarly in fish and mammals, despite significant physiological differences. Here, we exposed European perch (Perca fluviatilis) to the benzodiazepine drug temazepam at a nominal concentration of 2 µg L−1 for 10...

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Bibliographic Details
Main Authors: Daniel Cerveny, Jerker Fick, Jonatan Klaminder, Michael G. Bertram, Tomas Brodin
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321003572