EGFR, p53, IDH-1 and MDM2 immunohistochemical analysis in glioblastoma: therapeutic and prognostic correlation

EGFR, p53, IDH-1 and MDM2 immunohistochemical analysis in glioblastoma: therapeutic and prognostic correlation

We studied 36 glioblastoma cases at HC-UNICAMP from 2008 to 2012 and classified the immunohistochemical distribution of the wild-type epidermal growth factor receptor (EGFR), mutated forms of p53 protein and isocitrate dehydrogenase-1 (IDH-1) and murine double protein 2 (MDM2). Immunostaining findin...

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Bibliographic Details
Main Authors: Richard Murdoch Montgomery, Luciano de Souza Queiroz, Fabio Rogerio
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2015-07-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
glioblastoma
neurocirurgia
temozolomida
imunoistoquímica
prognóstico clínico
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700561&lng=en&tlng=en

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