Toxic epidermal necrosis syndrome after taking nonsteroidal antiinflammatory drugs: a case report

• Main Authors: Ezzat Allah Rahimi, Reza Ghanei Gheshlagh, Fazel Dehvan
• Format: Article
• Language: fas
• Published: Kurdistan University of Medical Sciences 2018-06-01
• Series: فصلنامه پرستاری،مامایی و پیراپزشکی
• Subjects: Toxic epidermal necrosis syndrome; Stevens Johnson syndrome; Nonsteroidal anti-inflammatory drugs
• Online Access: http://sjnmp.muk.ac.ir/browse.php?a_code=A-10-90-2&slc_lang=en&sid=1

Introduction: Toxic epidermal necrolysis (TEN) is among the most severe forms of dermatological reactions, which often occurs in response to non-steroidal anti-inflammatory drugs (NSAIDs) and leads to death in 20-50% of the cases.  Case Presentation: A 41-year-old male patient was referred with a history of NSAID use, presenting with maculopapular rashes, at Kowsar Hospital in Sanandaj, Iran. The patient was hospitalized and received various therapies. He was discharged after 14 days in a good overall condition.  Conclusion: Determining the basic etiology and disruption of pharmaceutical factors are essential to the treatment of TEN. The therapeutic interventions are similar to those used for burn patients. Keywords: Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome, Non-steroidal Anti-inflammatory Drugs