Essential Role for endogenous siRNAs during meiosis in mouse oocytes.

The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mammals, there are four AGO proteins (AGO1-4), of whi...

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Bibliographic Details
Main Authors: Paula Stein, Nikolay V Rozhkov, Fan Li, Fabián L Cárdenas, Olga Davydenko, Lee E Vandivier, Brian D Gregory, Gregory J Hannon, Richard M Schultz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4335007?pdf=render

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