Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system

Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radio...

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Main Authors: C. Guardiola, A. Márquez, M. C. Jiménez-Ramos, J. García López, A. Baratto-Roldán, X. Muñoz-Berbel
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89602-9
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spelling doaj-36c6904a35d24ba08f20d42db067cabf2021-05-23T11:33:02ZengNature Publishing GroupScientific Reports2045-23222021-05-0111111110.1038/s41598-021-89602-9Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical systemC. Guardiola0A. Márquez1M. C. Jiménez-Ramos2J. García López3A. Baratto-Roldán4X. Muñoz-Berbel5Université Paris‒Saclay, CNRS/IN2P3, IJCLabInstituto de Microelectrónica de Barcelona, (IMB-CNM, CSIC)Centro Nacional de AceleradoresCentro Nacional de AceleradoresCentro Nacional de AceleradoresInstituto de Microelectrónica de Barcelona, (IMB-CNM, CSIC)Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications.https://doi.org/10.1038/s41598-021-89602-9
collection DOAJ
language English
format Article
sources DOAJ
author C. Guardiola
A. Márquez
M. C. Jiménez-Ramos
J. García López
A. Baratto-Roldán
X. Muñoz-Berbel
spellingShingle C. Guardiola
A. Márquez
M. C. Jiménez-Ramos
J. García López
A. Baratto-Roldán
X. Muñoz-Berbel
Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
Scientific Reports
author_facet C. Guardiola
A. Márquez
M. C. Jiménez-Ramos
J. García López
A. Baratto-Roldán
X. Muñoz-Berbel
author_sort C. Guardiola
title Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_short Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_fullStr Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_full_unstemmed Dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
title_sort dosimetry with gafchromic films based on a new micro-opto-electro-mechanical system
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-05-01
description Abstract This work presents the first tests performed with radiochromic films and a new Micro‒Opto‒Electro-Mechanical system (MOEMS) for in situ dosimetry evaluation in radiotherapy in real time. We present a new device and methodology that overcomes the traditional limitation of time-delay in radiochromic film analysis by turning a passive detector into an active sensor. The proposed system consists mainly of an optical sensor based on light emitting diodes and photodetectors controlled by both customized electronic circuit and graphical user interface, which enables optical measurements directly. We show the first trials performed in a low‒energy proton cyclotron with this MOEMS by using gafchromic EBT3 films. Results show the feasibility of using this system for in situ dose evaluations. Further adaptation is ongoing to develop a full real‒time active detector by integrating MOEM multi‒arrays and films in flexible printed circuits. Hence, we point to improve the clinical application of radiochromic films with the aim to optimize radiotherapy treatment verifications.
url https://doi.org/10.1038/s41598-021-89602-9
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