Network analysis of metabolic enzyme evolution in <it>Escherichia coli</it>
<p>Abstract</p> <p>Background</p> <p>The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate specificity, and the retrograde evolution model, according to which enz...
Main Authors: | Kraulis Per, Light Sara |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-02-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/5/15 |
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