Premetazoan Origin of the Hippo Signaling Pathway

Premetazoan Origin of the Hippo Signaling Pathway

Nonaggregative multicellularity requires strict control of cell number. The Hippo signaling pathway coordinates cell proliferation and apoptosis and is a central regulator of organ size in animals. Recent studies have shown the presence of key members of the Hippo pathway in nonbilaterian animals,...

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Bibliographic Details
Main Authors: Arnau Sebé-Pedrós, Yonggang Zheng, Iñaki Ruiz-Trillo, Duojia Pan
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471100009X

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