Gastric pH in Rats: Key Determinant for Preclinical Evaluation of pH-dependent Oral Drug Absorption
Data on gastric pH in rats to be used in preclinical models for pH-dependent drug absorption are still limited or contradictory. The aim of this study was to describe gastric pH in rats at fasted state and to evaluate its changes induced by pentagastrin or omeprazole in order to mimic gastric pH at...
Main Authors: | Martin Šíma, Nikolina Kutinová-Canová, Pavel Ryšánek, Jana Hořínková, Denisa Moškořová, Ondřej Slanař |
---|---|
Format: | Article |
Language: | English |
Published: |
Karolinum Press
2019-01-01
|
Series: | Prague Medical Report |
Subjects: | |
Online Access: | https://pmr.lf1.cuni.cz/120/1/0005/ |
Similar Items
-
Which is More Effective in Altering the Intra-Gastric pH in Dogs, Omeprazole or Ranitidine?
by: Adam Swallow
Published: (2016-05-01) -
Traffic Noise Exposure Increases Gastric Pepsin Secretion in Rat
by: Azam Moslehi, et al.
Published: (2016-04-01) -
Avaliação do pH gástrico de cães tratados com omeprazol – estudo experimental
by: Bonfá, Laila de Paula
Published: (2015) -
Traffic Noise Exposure Increases Gastric Acid Secretion in Rat
by: Azam Moslehi, et al.
Published: (2010-04-01) -
Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH
by: Iida Hiroshi, et al.
Published: (2012-03-01)