Chronic Heroin Dependence Leading to Adrenal Insufficiency

Chronic Heroin Dependence Leading to Adrenal Insufficiency

Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and...

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Main Author: Gautam Das
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/461816
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spelling doaj-36ac1d47f38143a0a81040c86cb530902020-11-24T22:38:05ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/461816461816Chronic Heroin Dependence Leading to Adrenal InsufficiencyGautam Das0Department of Diabetes and Endocrinology, Prince Charles Hospital, Cwm Taf NHS Trust, Gurnos, Merthyr Tydfil, CF47 9DT, UKOpioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.http://dx.doi.org/10.1155/2014/461816
collection DOAJ
language English
format Article
sources DOAJ
author Gautam Das
spellingShingle Gautam Das
Chronic Heroin Dependence Leading to Adrenal Insufficiency
Case Reports in Endocrinology
author_facet Gautam Das
author_sort Gautam Das
title Chronic Heroin Dependence Leading to Adrenal Insufficiency
title_short Chronic Heroin Dependence Leading to Adrenal Insufficiency
title_full Chronic Heroin Dependence Leading to Adrenal Insufficiency
title_fullStr Chronic Heroin Dependence Leading to Adrenal Insufficiency
title_full_unstemmed Chronic Heroin Dependence Leading to Adrenal Insufficiency
title_sort chronic heroin dependence leading to adrenal insufficiency
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2014-01-01
description Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.
url http://dx.doi.org/10.1155/2014/461816
work_keys_str_mv AT gautamdas chronicheroindependenceleadingtoadrenalinsufficiency
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