Screening of abdominal obesity and diabetes mellitus in women with oncological diseases

• Main Authors: N.O. Pertseva, M.K. Rokutova, V.V. Melnik
• Format: Article
• Language: English
• Published: Publishing House Zaslavsky 2017-11-01
• Series: Mìžnarodnij Endokrinologìčnij Žurnal
• Subjects: abdominal obesity; oncological diseases; type 2 diabetes mellitus; insulin resistance; waist-to-height ratio; people of young and middle age
• Online Access: http://iej.zaslavsky.com.ua/article/view/119275
• ISSN: 2224-0721; 2307-1427

Background. The purpose of the study was to assess the presence of excess body weight, abdominal obesity (AO), and type 2 diabetes mellitus (DM) in oncological diseases in women of young and middle age. Materials and methods. 32 outpatient women aged 31 to 59 years with a verified oncological disease were examined. Standard clinical methods of investigation, statistical processing of results by nonparametric statistics were used. Results. Cervical cancer was verified in 24 (75.0 %) persons, breast adenocarcinoma — in 5 (15.6 %), rectal cancer — in 3 (9.4 %) patients. Elevated body mass index was detected in 24 (75.0 %) women: excess body weight — in 11 (34.4%), AO stage I — in 8 (25.0%), stage II — in 5 persons (15.6 %). Overweight or AO were detected in 30 (93.8 %) patients according to waist-to-height ratio. Type 2 DM was detected only in 2 patients (6.3 %). A heredity in oncopathology was recorded in half of women, of them for AO — in 8 (25.0 %), for type 2 DM — in 5 (15.6 %) patients. A direct correlation was established between heredity in oncological disease and body weight (r = 0.62, p < 0.01), waist circumference (r = 0.61, p < 0.01), body mass index (r = 0.66, p < 0.01), waist-to-height ratio (r = 0.49, p <0.05), waist circumference/hip circumference ratio (r = 0.41, p < 0.01). Conclusions. Overweight and obesity are common among women with cancer, especially, with cervical cancer. Correlation between increased anthropometric indicators and a family history of oncological diseases among women was noted. For comprehensive diagnosis of overweight, in addition to the standard anthropometric indicators, the waist-to-height ratio should be used, as well as additional examinations to detect type 2 DM, insulin resistance, metabolic changes.