ALT: A Multi-Faceted Phenomenon

One of the hallmarks of cancer cells is their indefinite replicative potential, made possible by the activation of a telomere maintenance mechanism (TMM). The majority of cancers reactivate the reverse transcriptase, telomerase, to maintain their telomere length but a minority (10% to 15%) utilize a...

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Bibliographic Details
Main Authors: Aurore Sommer, Nicola J. Royle
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/2/133