Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells

Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells

Citrobacter rodentium infection is a murine model for pathogenic intestinal Escherichia coli infection. C. rodentium infection causes an initial decrease in mucus layer thickness, followed by an increase during clearance. We aimed to identify the cause of these changes and to utilize this naturally...

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Bibliographic Details
Main Authors: S. Sharba, N. Navabi, M. Padra, J. A. Persson, M. P. Quintana-Hayashi, J. K. Gustafsson, L. Szeponik, V. Venkatakrishnan, Å. Sjöling, S. Nilsson, M. Quiding-Järbrink, M. E. V. Johansson, S. K. Linden
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Virulence
Subjects:
mucin
mucus
mucosa
citrobacter rodentium
a/e pathogen
cytokine
il-4
ifn-γ
colitis
host-pathogen interaction
Online Access:http://dx.doi.org/10.1080/21505594.2019.1573050

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