Diet-induced obesity promotes colon tumor development in azoxymethane-treated mice.

Obesity is an important risk factor for colon cancer in humans, and numerous studies have shown that a high fat diet enhances colon cancer development. As both increased adiposity and high fat diet can promote tumorigenesis, we examined the effect of diet-induced obesity, without ongoing high fat di...

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Bibliographic Details
Main Authors: Iina Tuominen, Leina Al-Rabadi, Dimitris Stavrakis, Iordanis Karagiannides, Charalabos Pothoulakis, James M Bugni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3616169?pdf=render