Molecular Signature of Small Cell Lung Cancer after Treatment Failure: The <i>MCM</i> Complex as Therapeutic Target

Molecular Signature of Small Cell Lung Cancer after Treatment Failure: The <i>MCM</i> Complex as Therapeutic Target

Small cell lung cancer (SCLC) is a highly aggressive cancer, and patients who become refractory to first-line treatment have a poor prognosis. The development of effective treatment regimens is urgently needed. In this study, we identified a gene expression signature of SCLC after treatment failure...

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Bibliographic Details
Main Authors: Shunsuke Misono, Keiko Mizuno, Takayuki Suetsugu, Kengo Tanigawa, Nijiro Nohata, Akifumi Uchida, Hiroki Sanada, Reona Okada, Shogo Moriya, Hiromasa Inoue, Naohiko Seki
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
small cell lung cancer
cell cycle pathway
<i>MCM2</i>
<i>MCM4</i>
<i>MCM6</i>
<i>MCM7</i>
Online Access:https://www.mdpi.com/2072-6694/13/6/1187

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