Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation

Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) with donor lymphocyte infusion is the mainstay of treatment for many types of hematological malignancies, but the therapeutic effect and prevention of relapse is complicated by donor T-cell recognition and attack of host tissue in a proc...

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Bibliographic Details
Main Authors: Todd V. Brennan, Victoria R. Rendell, Yiping eYang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00101/full