Protective role of antioxidant vitamin E and catechin on idarubicin-induced cardiotoxicity in rats

Protective role of antioxidant vitamin E and catechin on idarubicin-induced cardiotoxicity in rats

Idarubicin is an anthracycline antibiotic extensively used in acute leukemia. In the present study we investigated whether vitamin E and catechin can reduce the toxic effects of idarubicin. Vitamin E (200 IU kg-1 week-1), catechin (200 mg kg-1 week-1), idarubicin (5 mg kg-1 week-1), idarubicin + vit...

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Bibliographic Details
Main Authors:	Kalender S., Kalender Y., Ates A., Yel M., Olcay E., Candan S.
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2002-01-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Idarubicin Catechin Vitamin E Cardiotoxicity Ultrastructure
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001100017

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