The Relationship between Matrix Metalloproteinase Gene Polymorphisms and Tumor Type, Tumor Size, and Metastasis in Women with Breast Cancer in Central Iran

The Relationship between Matrix Metalloproteinase Gene Polymorphisms and Tumor Type, Tumor Size, and Metastasis in Women with Breast Cancer in Central Iran

Background: Matrix metalloproteinases-2 and -9 play important roles in the development of breast cancer by hydrolyzing the extracellular matrix. Since −1306C/T and −1562C/T polymorphisms are located at the promoter regions of the matrix metalloproteinase- 2 and -9 genes, respectively, C to T substit...

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Bibliographic Details
Main Authors: Zahra Dehghan Manshadi, Mohammad Hamid, Farid Kosari, Heidar Tayebinia, Iraj Khodadadi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-04-01
Series:Middle East Journal of Cancer
Subjects:
Breast neoplasms
Matrix metalloproteinases
Neoplasm metastasis
Single nucleotide polymorphism
Online Access:http://mejc.sums.ac.ir/index.php/mejc/article/view/646

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