Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells

Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells

Summary It has previously been demonstrated that cell shape can influence commitment of human bone marrow-derived mesenchymal stem cells (hBMCs) to adipogenic, osteogenic, chondrogenic, and other lineages. Human periosteum-derived cells (hPDCs) exhibit multipotency similar to hBMCs, but hPDCs may of...

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Bibliographic Details
Main Authors: Jeroen Eyckmans, Grace L. Lin, Christopher S. Chen
Format: Article
Language:English
Published: The Company of Biologists 2012-08-01
Series:Biology Open
Subjects:
Mesenchymal stem cell differentiation
Mechanoregulation
Cell shape
Rho kinase
Adhesion
Online Access:http://bio.biologists.org/content/1/11/1058

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