Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity

Laser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology. Biosensors with various gold film porosities were tested u...

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Main Authors:	Dana Miu, Izabela Constantinoiu, Valentina Dinca, Cristian Viespe
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Chemosensors
Subjects:	SAW sensor pulsed laser deposition biosensor Au nanoporous film love wave
Online Access:	https://www.mdpi.com/2227-9040/9/7/173

id	doaj-361d256d3c80456fa32e0db75a1548cc
record_format	Article
spelling	doaj-361d256d3c80456fa32e0db75a1548cc2021-07-23T13:35:28ZengMDPI AGChemosensors2227-90402021-07-01917317310.3390/chemosensors9070173Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled PorosityDana Miu0Izabela Constantinoiu1Valentina Dinca2Cristian Viespe3Laser Department, National Institute for Laser, Plasma and Radiation Physics, Atomistilor 409, 077125 Magurele, RomaniaLaser Department, National Institute for Laser, Plasma and Radiation Physics, Atomistilor 409, 077125 Magurele, RomaniaLaser Department, National Institute for Laser, Plasma and Radiation Physics, Atomistilor 409, 077125 Magurele, RomaniaLaser Department, National Institute for Laser, Plasma and Radiation Physics, Atomistilor 409, 077125 Magurele, RomaniaLaser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology. Biosensors with various gold film porosities were tested using the biotin–avidin reaction. Control of the Au layer morphology is important since the biotin and avidin layer morphologies closely follow that of the gold. The response of the sensors to biotin/avidin, which is a good indicator of biosensor performance, is improved when the gold layer has increased porosity. Given the sizes of the proteins, the laser-deposited porous gold interfaces have optimal pore dimensions to ensure protein stability.https://www.mdpi.com/2227-9040/9/7/173SAW sensorpulsed laser depositionbiosensorAunanoporous filmlove wave
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Dana Miu Izabela Constantinoiu Valentina Dinca Cristian Viespe
spellingShingle	Dana Miu Izabela Constantinoiu Valentina Dinca Cristian Viespe Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity Chemosensors SAW sensor pulsed laser deposition biosensor Au nanoporous film love wave
author_facet	Dana Miu Izabela Constantinoiu Valentina Dinca Cristian Viespe
author_sort	Dana Miu
title	Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
title_short	Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
title_full	Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
title_fullStr	Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
title_full_unstemmed	Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
title_sort	surface acoustic wave biosensor with laser-deposited gold layer having controlled porosity
publisher	MDPI AG
series	Chemosensors
issn	2227-9040
publishDate	2021-07-01
description	Laser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology. Biosensors with various gold film porosities were tested using the biotin–avidin reaction. Control of the Au layer morphology is important since the biotin and avidin layer morphologies closely follow that of the gold. The response of the sensors to biotin/avidin, which is a good indicator of biosensor performance, is improved when the gold layer has increased porosity. Given the sizes of the proteins, the laser-deposited porous gold interfaces have optimal pore dimensions to ensure protein stability.
topic	SAW sensor pulsed laser deposition biosensor Au nanoporous film love wave
url	https://www.mdpi.com/2227-9040/9/7/173
work_keys_str_mv	AT danamiu surfaceacousticwavebiosensorwithlaserdepositedgoldlayerhavingcontrolledporosity AT izabelaconstantinoiu surfaceacousticwavebiosensorwithlaserdepositedgoldlayerhavingcontrolledporosity AT valentinadinca surfaceacousticwavebiosensorwithlaserdepositedgoldlayerhavingcontrolledporosity AT cristianviespe surfaceacousticwavebiosensorwithlaserdepositedgoldlayerhavingcontrolledporosity
_version_	1721288868131504128

Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity

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