Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli

Metabolic engineering requires fine-tuned gene expression for most pathway optimization applications. To develop a suitable suite of promoters, traditional bacterial promoter engineering efforts have focused on modifications to the core region, especially the −10 and −35 regions, of native promoters...

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Bibliographic Details
Main Authors: Kristin V. Presnell, Madeleine Flexer-Harrison, Hal S. Alper
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-06-01
Series:Synthetic and Systems Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X18300954