Evaluation of Bioinformatics Approaches for Next-Generation Sequencing Analysis of microRNAs with a Toxicogenomics Study Design

MicroRNAs (miRNAs) are key post-transcriptional regulators that affect protein translation by targeting mRNAs. Their role in disease etiology and toxicity are well recognized. Given the rapid advancement of next-generation sequencing techniques, miRNA profiling has been increasingly conducted with R...

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Bibliographic Details
Main Authors: Halil Bisgin, Binsheng Gong, Yuping Wang, Weida Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00022/full