In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent

Background: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However...

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Main Authors: Bayram METİN, Neziha YILMAZ, Yunus Emre BEYHAN, Cahit BABÜR, Mesut SİPAHİ, Hüseyin EDE, Yavuz Selim İNTEPE, Ergin ARSLAN, Tugay ATALAY, Mustafa Yaşar ÖZDAMAR
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-12-01
Series:Iranian Journal of Parasitology
Subjects:
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1213
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spelling doaj-360cb62a2c194126bb25f54bcfc98fec2021-04-02T18:14:05ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2016-12-01113601In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal AgentBayram METİN0Neziha YILMAZ1Yunus Emre BEYHAN2Cahit BABÜR3Mesut SİPAHİ4Hüseyin EDE5Yavuz Selim İNTEPE6Ergin ARSLAN7Tugay ATALAY8Mustafa Yaşar ÖZDAMAR9Department of Thoracic Surgery, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of Infectious Diseases, Faculty of Medicine, Bozok University, Yozgat, TurkeyDivision of Public Health Affairs, Ministry of Health, Ankara, TurkeyDivision of Public Health Affairs, Ministry of Health, Ankara, TurkeyDepartment of Chest Diseases, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of General Surgery, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of Cardiology, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of Chest Diseases, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of Neurosurgery, Faculty of Medicine, Bozok University, Yozgat, TurkeyDepartment of Pediatric Surgery, Faculty of Medicine, Bozok University, Yozgat, Turkey Background: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However, the germicidal efficacy of the Ankaferd Blood Stopper® (ABS) has not been investigated. Thus, we compared the efficacy of ABS for hydatid cysts with that of other germicidal agents. Methods: Lung and liver tissues containing hydatid cyst liquid were collected from slaughterhouses. Six samples of each cyst were randomly allocated into different groups as follows: 20% hypertonic NaCl, betadine solution, ABS, 20% liquefied Andazole solution, 0.1% eosin, and distilled water. All groups were examined microscopically at 5, 10, and 15 min after treatment began to determine protoscolece viability rates. Results: The most efficacious germicidal agent at 5 min was ABS, and betadine and hypertonic NaCl had similar efficacies. Betadine, ABS, and hypertonic NaCl showed similar efficacies at 15 min.  Conclusion: ABS was an effective germicidal agent to treat hydatid cysts. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1213Hydatid cystGermicidal agentAnkaferd blood stopper
collection DOAJ
language English
format Article
sources DOAJ
author Bayram METİN
Neziha YILMAZ
Yunus Emre BEYHAN
Cahit BABÜR
Mesut SİPAHİ
Hüseyin EDE
Yavuz Selim İNTEPE
Ergin ARSLAN
Tugay ATALAY
Mustafa Yaşar ÖZDAMAR
spellingShingle Bayram METİN
Neziha YILMAZ
Yunus Emre BEYHAN
Cahit BABÜR
Mesut SİPAHİ
Hüseyin EDE
Yavuz Selim İNTEPE
Ergin ARSLAN
Tugay ATALAY
Mustafa Yaşar ÖZDAMAR
In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
Iranian Journal of Parasitology
Hydatid cyst
Germicidal agent
Ankaferd blood stopper
author_facet Bayram METİN
Neziha YILMAZ
Yunus Emre BEYHAN
Cahit BABÜR
Mesut SİPAHİ
Hüseyin EDE
Yavuz Selim İNTEPE
Ergin ARSLAN
Tugay ATALAY
Mustafa Yaşar ÖZDAMAR
author_sort Bayram METİN
title In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_short In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_full In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_fullStr In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_full_unstemmed In Vitro Efficacy of the Ankaferd Galenic Hemostatic Extract as a Germicidal Agent
title_sort in vitro efficacy of the ankaferd galenic hemostatic extract as a germicidal agent
publisher Tehran University of Medical Sciences
series Iranian Journal of Parasitology
issn 1735-7020
2008-238X
publishDate 2016-12-01
description Background: Hydatid cysts are encountered frequently in regions endemic with livestock. The basic treatment for a hydatid cyst is total surgical removal of the cyst and its inner contents. Hypertonic NaCl or diluted betadine solution are used as germicidal agents for most hydatid surgeries. However, the germicidal efficacy of the Ankaferd Blood Stopper® (ABS) has not been investigated. Thus, we compared the efficacy of ABS for hydatid cysts with that of other germicidal agents. Methods: Lung and liver tissues containing hydatid cyst liquid were collected from slaughterhouses. Six samples of each cyst were randomly allocated into different groups as follows: 20% hypertonic NaCl, betadine solution, ABS, 20% liquefied Andazole solution, 0.1% eosin, and distilled water. All groups were examined microscopically at 5, 10, and 15 min after treatment began to determine protoscolece viability rates. Results: The most efficacious germicidal agent at 5 min was ABS, and betadine and hypertonic NaCl had similar efficacies. Betadine, ABS, and hypertonic NaCl showed similar efficacies at 15 min.  Conclusion: ABS was an effective germicidal agent to treat hydatid cysts.
topic Hydatid cyst
Germicidal agent
Ankaferd blood stopper
url https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1213
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