Trans-translation exposed: understanding the structures and functions of tmRNA-SmpB

Ribosome stalling is a serious issue for cell survival. In bacteria, the primary rescue system is trans-translation, performed by tmRNA and its protein partner small protein B (SmpB). Since its discovery almost 20 years ago, biochemical, genetic, and structural studies have paved the way to a better...

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Bibliographic Details
Main Authors: Emmanuel eGIUDICE, Kevin eMACE, Reynald eGILLET
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00113/full