Centrosome-associated regulators of the G<sub>2</sub>/M checkpoint as targets for cancer therapy

<p>Abstract</p> <p>In eukaryotic cells, control mechanisms have developed that restrain cell-cycle transitions in response to stress. These regulatory pathways are termed cell-cycle checkpoints. The G<sub>2</sub>/M checkpoint prevents cells from entering mitosis when DN...

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Bibliographic Details
Main Authors: Broaddus Russell R, Liu Jinsong, Ji Ping, Wang Yingmei, Xue Fengxia, Zhang Wei
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/8