Bifunctional inhibitors of urokinase and metalloproteinase-9 for cancer treatment - in silico evaluation
Matrix metalloproteinase-9 (MMP-9), and urokinase plasminogen activator (uPA) overexpression or/and increased activity are considered causative elements for cancer invasion and metastasis. These enzymes are degrading the extracellular matrix (ECM) providing space for cancer progression and cancer ce...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The University of Toledo
2018-09-01
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| Series: | Translation |
| Online Access: | https://openjournals.utoledo.edu/index.php/translation/article/view/243 |