Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up

Flow diverters (FDs) are designed for the endovascular treatment of complex intracranial aneurysm configurations. From February 2009 to March 2013 28 patients (22 females, 6 males) were treated with FD; mean age was 57 years. Data, including aneurysm features, clinical presentation, history of previ...

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Main Authors: Anna-Katharina Breu, Till-Karsten Hauser, Florian H. Ebner, Felix Bischof, Ulrike Ernemann, Achim Seeger
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/2187275
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spelling doaj-35dd780ec3604bec871f48ec979807062020-11-25T00:53:36ZengHindawi LimitedRadiology Research and Practice2090-19412090-195X2016-01-01201610.1155/2016/21872752187275Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-UpAnna-Katharina Breu0Till-Karsten Hauser1Florian H. Ebner2Felix Bischof3Ulrike Ernemann4Achim Seeger5Department of Diagnostic and Interventional Neuroradiology, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyDepartment of Neurosurgery, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyDepartment of Neurology, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyDepartment of Diagnostic and Interventional Neuroradiology, Eberhard Karls University, Hoppe-Seyler-Street 3, 72076 Tübingen, GermanyFlow diverters (FDs) are designed for the endovascular treatment of complex intracranial aneurysm configurations. From February 2009 to March 2013 28 patients (22 females, 6 males) were treated with FD; mean age was 57 years. Data, including aneurysm features, clinical presentation, history of previous bleeding, treatment, and follow-up results, are presented. Early postinterventional neurological deficits (transient: n=3/enduring: n=1) appeared in 4/28 patients (14%), and early improvement of neurological symptoms was observed in 7 patients with previous restriction of cranial nerve function. The overall occlusion rate was 20/26 (77%; 59% after 3 months). 77% achieved best results according to O’Kelly-Marotta score grade D with no contrast material filling (70% of those after 3 months). In 4/6 patients who did not achieve grade D, proximal and/or distal stent overlapping ≥5 mm was not guaranteed sufficiently. During follow-up we did not detect any aneurysm recurrence or haemorrhage. In-stent stenosis emerged as the most frequent complication (4/27; 15%) followed by 2 cases of vascular obliteration (AICA/VA). In conclusion endovascular reconstruction using a FD represents a modern and effective treatment in those aneurysms that are not suitable for conventional interventional or surgical treatment. The appearance of severe complications was rare.http://dx.doi.org/10.1155/2016/2187275
collection DOAJ
language English
format Article
sources DOAJ
author Anna-Katharina Breu
Till-Karsten Hauser
Florian H. Ebner
Felix Bischof
Ulrike Ernemann
Achim Seeger
spellingShingle Anna-Katharina Breu
Till-Karsten Hauser
Florian H. Ebner
Felix Bischof
Ulrike Ernemann
Achim Seeger
Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
Radiology Research and Practice
author_facet Anna-Katharina Breu
Till-Karsten Hauser
Florian H. Ebner
Felix Bischof
Ulrike Ernemann
Achim Seeger
author_sort Anna-Katharina Breu
title Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
title_short Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
title_full Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
title_fullStr Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
title_full_unstemmed Morphologic and Clinical Outcome of Intracranial Aneurysms after Treatment Using Flow Diverter Devices: Mid-Term Follow-Up
title_sort morphologic and clinical outcome of intracranial aneurysms after treatment using flow diverter devices: mid-term follow-up
publisher Hindawi Limited
series Radiology Research and Practice
issn 2090-1941
2090-195X
publishDate 2016-01-01
description Flow diverters (FDs) are designed for the endovascular treatment of complex intracranial aneurysm configurations. From February 2009 to March 2013 28 patients (22 females, 6 males) were treated with FD; mean age was 57 years. Data, including aneurysm features, clinical presentation, history of previous bleeding, treatment, and follow-up results, are presented. Early postinterventional neurological deficits (transient: n=3/enduring: n=1) appeared in 4/28 patients (14%), and early improvement of neurological symptoms was observed in 7 patients with previous restriction of cranial nerve function. The overall occlusion rate was 20/26 (77%; 59% after 3 months). 77% achieved best results according to O’Kelly-Marotta score grade D with no contrast material filling (70% of those after 3 months). In 4/6 patients who did not achieve grade D, proximal and/or distal stent overlapping ≥5 mm was not guaranteed sufficiently. During follow-up we did not detect any aneurysm recurrence or haemorrhage. In-stent stenosis emerged as the most frequent complication (4/27; 15%) followed by 2 cases of vascular obliteration (AICA/VA). In conclusion endovascular reconstruction using a FD represents a modern and effective treatment in those aneurysms that are not suitable for conventional interventional or surgical treatment. The appearance of severe complications was rare.
url http://dx.doi.org/10.1155/2016/2187275
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