KIT ligand protects against both light-induced and genetic photoreceptor degeneration

KIT ligand protects against both light-induced and genetic photoreceptor degeneration

Photoreceptor degeneration is a major cause of blindness and a considerable health burden during aging but effective therapeutic or preventive strategies have not so far become readily available. Here, we show in mouse models that signaling through the tyrosine kinase receptor KIT protects photorece...

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Bibliographic Details
Main Authors: Huirong Li, Lili Lian, Bo Liu, Yu Chen, Jinglei Yang, Shuhui Jian, Jiajia Zhou, Ying Xu, Xiaoyin Ma, Jia Qu, Ling Hou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
endogenous neuroprotection
tyrosine kinase receptor
stem cell factor
retinitis pigmentosa
antioxidative
Online Access:https://elifesciences.org/articles/51698

Internet

https://elifesciences.org/articles/51698

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