Prion protein accumulation in lipid rafts of mouse aging brain.

The cellular form of the prion protein (PrP(C)) is a normal constituent of neuronal cell membranes. The protein misfolding causes rare neurodegenerative disorders known as transmissible spongiform encephalopathies or prion diseases. These maladies can be sporadic, genetic or infectious. Sporadic pri...

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Bibliographic Details
Main Authors: Federica Agostini, Carlos G Dotti, Azucena Pérez-Cañamás, Maria Dolores Ledesma, Federico Benetti, Giuseppe Legname
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769255?pdf=render