Human NKG2D-ligands: cell biology strategies to ensure immune recognition

Immune recognition mediated by the activating receptor NKG2D plays an important role for the elimination of stressed cells, including tumours and virus-infected cells. On the other hand, the ligands for NKG2D can also be shed into the sera of cancer patients where they weaken the immune response by...

Full description

Bibliographic Details
Main Authors: Lola eFernández-Messina, Hugh T. Reyburn, Mar eVales-Gomez
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00299/full