A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy

Bart J Crielaard1, Steffen van der Wal1, Twan Lammers2, Huong Thu Le1, Wim E Hennink1, Raymond M Schiffelers1, Gert Storm1, Marcel HAM Fens11Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; 2Department of Experimental Molecular...

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Bibliographic Details
Main Authors: Crielaard BJ, van der Wal S, Lammers T, Le HT, Hennink WE, Schiffelers RM, Storm G, Fens MHAM
Format: Article
Language:English
Published: Dove Medical Press 2011-11-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/a-polymeric-colchicinoid-prodrug-with-reduced-toxicity-and-improved-ef-a8587