Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide

Synthesis, spectroscopic characterization and X-ray crystal structure of a new (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide (4) are reported. The stereochemistry of the title compound 4, C19H19N5O, about the imine bond [1.296 (4) Å] was assigned to have (E)-configur...

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Main Authors:	Mohamed I. Attia, Hazem A. Ghabbour, Aida A. El-Azzouny, Omar A. Al-Deeb, Maha S. Almutairi, Hoong-Kun Fun
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2013/515309

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spelling	doaj-35c171a3157b4c28800018407c4e8a842020-11-24T23:54:15ZengHindawi LimitedJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/515309515309Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamideMohamed I. Attia0Hazem A. Ghabbour1Aida A. El-Azzouny2Omar A. Al-Deeb3Maha S. Almutairi4Hoong-Kun Fun5Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi ArabiaMedicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Giza 12622, EgyptDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi ArabiaSynthesis, spectroscopic characterization and X-ray crystal structure of a new (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide (4) are reported. The stereochemistry of the title compound 4, C19H19N5O, about the imine bond [1.296 (4) Å] was assigned to have (E)-configuration. In the urea moiety, the N–H entities are trans to each other, and one of these forms is an intramolecular N–H⋯H hydrogen bond. The compound crystallizes in the monoclinic space group P21/c with a = 5.8093 (2) Å, b = 20.5575 (6) Å, c = 14.0355 (5) Å, α = 90.00°, β = 97.365° (2), γ = 90.00°, V = 1662.36 (10) Å3, and Z = 4. The molecules are packed in crystal structure by weak intermolecular hydrogen interactions.http://dx.doi.org/10.1155/2013/515309
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Mohamed I. Attia Hazem A. Ghabbour Aida A. El-Azzouny Omar A. Al-Deeb Maha S. Almutairi Hoong-Kun Fun
spellingShingle	Mohamed I. Attia Hazem A. Ghabbour Aida A. El-Azzouny Omar A. Al-Deeb Maha S. Almutairi Hoong-Kun Fun Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide Journal of Chemistry
author_facet	Mohamed I. Attia Hazem A. Ghabbour Aida A. El-Azzouny Omar A. Al-Deeb Maha S. Almutairi Hoong-Kun Fun
author_sort	Mohamed I. Attia
title	Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
title_short	Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
title_full	Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
title_fullStr	Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
title_full_unstemmed	Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
title_sort	synthesis and single crystal x-ray structure of new (2e)-2-[3-(1h-imidazol-1-yl)-1-phenylpropylidene]-n-phenylhydrazinecarboxamide
publisher	Hindawi Limited
series	Journal of Chemistry
issn	2090-9063 2090-9071
publishDate	2013-01-01
description	Synthesis, spectroscopic characterization and X-ray crystal structure of a new (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide (4) are reported. The stereochemistry of the title compound 4, C19H19N5O, about the imine bond [1.296 (4) Å] was assigned to have (E)-configuration. In the urea moiety, the N–H entities are trans to each other, and one of these forms is an intramolecular N–H⋯H hydrogen bond. The compound crystallizes in the monoclinic space group P21/c with a = 5.8093 (2) Å, b = 20.5575 (6) Å, c = 14.0355 (5) Å, α = 90.00°, β = 97.365° (2), γ = 90.00°, V = 1662.36 (10) Å3, and Z = 4. The molecules are packed in crystal structure by weak intermolecular hydrogen interactions.
url	http://dx.doi.org/10.1155/2013/515309
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Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide

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