HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

Human Cytomegalovirus (HCMV) infection induces several metabolic activities that have been found to be important for viral replication. The cellular AMP-activated protein kinase (AMPK) is a metabolic stress response kinase that regulates both energy-producing catabolic processes and energy-consuming...

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Bibliographic Details
Main Authors: Jessica McArdle, Nathaniel J Moorman, Joshua Munger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3266935?pdf=render

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