Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft corona proteins and investigate the effects on cell int...

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Main Authors:	Hossein Mohammad-Beigi, Yuya Hayashi, Christina Moeslund Zeuthen, Hoda Eskandari, Carsten Scavenius, Kristian Juul-Madsen, Thomas Vorup-Jensen, Jan J. Enghild, Duncan S. Sutherland
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-18237-7

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spelling	doaj-35b5008eb572436fb96cdcb7e530c5c02021-09-12T11:48:38ZengNature Publishing GroupNature Communications2041-17232020-09-0111111610.1038/s41467-020-18237-7Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular associationHossein Mohammad-Beigi0Yuya Hayashi1Christina Moeslund Zeuthen2Hoda Eskandari3Carsten Scavenius4Kristian Juul-Madsen5Thomas Vorup-Jensen6Jan J. Enghild7Duncan S. Sutherland8Interdisciplinary Nanoscience Centre (iNANO), Aarhus UniversityDepartment of Molecular Biology and Genetics, Aarhus UniversityInterdisciplinary Nanoscience Centre (iNANO), Aarhus UniversityInterdisciplinary Nanoscience Centre (iNANO), Aarhus UniversityDepartment of Molecular Biology and Genetics, Aarhus UniversityDepartment of Biomedicine, Faculty of Health, Aarhus UniversityDepartment of Biomedicine, Faculty of Health, Aarhus UniversityDepartment of Molecular Biology and Genetics, Aarhus UniversityInterdisciplinary Nanoscience Centre (iNANO), Aarhus UniversityUnderstanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft corona proteins and investigate the effects on cell interactions.https://doi.org/10.1038/s41467-020-18237-7
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hossein Mohammad-Beigi Yuya Hayashi Christina Moeslund Zeuthen Hoda Eskandari Carsten Scavenius Kristian Juul-Madsen Thomas Vorup-Jensen Jan J. Enghild Duncan S. Sutherland
spellingShingle	Hossein Mohammad-Beigi Yuya Hayashi Christina Moeslund Zeuthen Hoda Eskandari Carsten Scavenius Kristian Juul-Madsen Thomas Vorup-Jensen Jan J. Enghild Duncan S. Sutherland Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association Nature Communications
author_facet	Hossein Mohammad-Beigi Yuya Hayashi Christina Moeslund Zeuthen Hoda Eskandari Carsten Scavenius Kristian Juul-Madsen Thomas Vorup-Jensen Jan J. Enghild Duncan S. Sutherland
author_sort	Hossein Mohammad-Beigi
title	Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
title_short	Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
title_full	Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
title_fullStr	Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
title_full_unstemmed	Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
title_sort	mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-09-01
description	Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft corona proteins and investigate the effects on cell interactions.
url	https://doi.org/10.1038/s41467-020-18237-7
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Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

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