Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft corona proteins and investigate the effects on cell int...

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Bibliographic Details
Main Authors: Hossein Mohammad-Beigi, Yuya Hayashi, Christina Moeslund Zeuthen, Hoda Eskandari, Carsten Scavenius, Kristian Juul-Madsen, Thomas Vorup-Jensen, Jan J. Enghild, Duncan S. Sutherland
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18237-7
Description
Summary:Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft corona proteins and investigate the effects on cell interactions.
ISSN:2041-1723

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