Dopaminergic drugs for the prevention of menstrual disorders in girls with autoimmune thyroiditis

• Main Authors: Л. В. Калугіна, І. В. Бачинська, Н. В. Яроцька
• Format: Article
• Language: English
• Published: Publishing House TRILIST 2018-12-01
• Series: Репродуктивная эндокринология
• Subjects: reproductive health; adolescence; autoimmune thyroiditis; prevention; menstrual disorders; cyclodynon
• Online Access: http://reproduct-endo.com/article/view/149302

A disbalance of hypothalamic-pituitary-ovarian relations is noted in adolescent girls with autoimmune thyroiditis, due to heightened prolactin, LH, cortisol, lowered estradiol, progesterone, accompanied by changes in the functional state of ovaries per data of echographs and with possible further disruptions of reproductive health. Multidisciplinary observation algorithm for euthyroid girls with autoimmune thyroiditis was proposed. 88 girls of late adolescence (58 – main group, 30 – comparison group), Vitex agnus-castus extract (1 tablet 1 time per day) and basic cyclic vitamin therapy, which is traditionally used in the practice of children’s gynecology: vitamin E – 200 mg, 1 capsule per day every second day, folic acid – 1 mg, 3 times per day on days 1–14 of the menstrual cycle, vitamin C – 100 mg, 2 times per day on 15–28 days of cycle. The girls of the comparison group was intended only cyclic vitamin therapy. Both surveyed groups received prophylactic correction for 3 months, the next assessment of the patient’s condition was performed after 3 months of further observation. with autoimmune thyroiditis allowed for improved hormonal status, ovarian functional state per echography. Following use of the proposed prophylactic complex there over nine months.