Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2i) as a Primary Preventative Agent in the Healthy Individual: A Need of a Future Randomised Clinical Trial?

Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2i) as a Primary Preventative Agent in the Healthy Individual: A Need of a Future Randomised Clinical Trial?

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are a relatively novel class of drug for treating type 2 diabetes mellitus (T2DM) that inhibits glucose reabsorption in the renal proximal tubule to promote glycosuria and reduce blood glucose levels. SGLT2i has been clinically indicated for treatin...

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Bibliographic Details
Main Authors: Dan Xu, Owain Chandler, Cleo Wee, Chau Ho, Jacquita S. Affandi, Daya Yang, Xinxue Liao, Wei Chen, Yanbing Li, Christopher Reid, Haipeng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
SGLT2i inhibitor
primary prevention
cardioprotection
renoprotection
chronic diseases prevention
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.712671/full

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