A clinical case of adult-onset Still's disease resistant to therapy with tumor necrosis factor-alpha inhibitors and interleukin-6 inhibitors

The basis of the clinical picture of adult-onset Still's disease is a triad of symptoms, includingfever, arthralgia/arthritis, and characteristic rash called «Still rash». The first line of therapy includes glucocorticoids, synthetic disease-modifying anti-rheumatic drugs; biological agents, su...

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Bibliographic Details
Main Authors: R. R. Samigullina, E. A. Vasilenko, V. I. Mazurov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2019-03-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/892
Description
Summary:The basis of the clinical picture of adult-onset Still's disease is a triad of symptoms, includingfever, arthralgia/arthritis, and characteristic rash called «Still rash». The first line of therapy includes glucocorticoids, synthetic disease-modifying anti-rheumatic drugs; biological agents, such as tumor necrosis factor a inhibitors and interleukin-6 and interleukin-1 inhibitors, are used in standard therapy-resistant cases.
ISSN:1996-7012
2310-158X