STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

Intestinal immune homeostasis is preserved by commensal bacteria interacting with the host to generate a balanced array of cytokines that are essential for wound repair and for combatting infection. Inflammatory bowel disease (IBD), which can lead to colitis-associated cancer (CAC), is thought to in...

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Bibliographic Details
Main Authors: Jeonghyun Ahn, Sehee Son, Sergio C. Oliveira, Glen N. Barber
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
STING
IL-10
inflammatory bowel disease
IBD
colitis-associated cancer
CAC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317850

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