Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels.

Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels.

G protein-gated inwardly rectifying potassium (GIRK) channels play an important role in regulating neuronal excitability. Sorting nexin 27b (SNX27b), which reduces surface expression of GIRK channels through a PDZ domain interaction, contains a putative Ras-association (RA) domain with unknown funct...

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Bibliographic Details
Main Authors: Bartosz Balana, Laia Bahima, Karthik Bodhinathan, Jaume J Taura, Natalie M Taylor, Margaret Y Nettleton, Francisco Ciruela, Paul A Slesinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3607560?pdf=render

Internet

http://europepmc.org/articles/PMC3607560?pdf=render

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