Experimental Model of Gene Transfection in Healthy Canine Myocardium: Perspectives of Gene Therapy for Ischemic Heart Disease

Experimental Model of Gene Transfection in Healthy Canine Myocardium: Perspectives of Gene Therapy for Ischemic Heart Disease

OBJECTIVE: To assess the transfection of the gene that encodes green fluorescent protein (GFP) through direct intramyocardial injection. METHODS: The pREGFP plasmid vector was used. The EGFP gene was inserted downstream from the constitutive promoter of the Rous sarcoma virus. Five male dogs were us...

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Bibliographic Details
Main Authors: Renato A. K. Kalil, Leonardo A. K. Teixeira, Eduardo T. Mastalir, Paulo Moreno, Cecília H. Fricke, Nance B. Nardi
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 2002-09-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
gene therapy
gene transfection
ischemic heart disease
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2002001200003

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