From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)

From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)

We report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bi...

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Main Authors: Marta F. Gabriel, Purificación González-Delgado, Idoia Postigo, Javier Fernández, Victor Soriano, Begoña Cueva, Jorge Martínez
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Medical Mycology Case Reports
Subjects:
Agaricus bisporus
Anaphylaxis
Cross-reactivity
Food allergy
Mold allergy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753915000081
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spelling doaj-35793ca259604e55876e18de99471d582020-11-25T03:35:48ZengElsevierMedical Mycology Case Reports2211-75392015-06-018C141610.1016/j.mmcr.2015.02.003From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)Marta F. Gabriel0Purificación González-Delgado1Idoia Postigo2Javier Fernández3Victor Soriano4Begoña Cueva5Jorge Martínez6Department of Immunology, Microbiology and Parasitology, Faculty of Pharmacy, Laboratory of Parasitology and Immunoallergy, Center for Research Laskaray, University of the Basque Country, Paseo Universidad, 6, 01006 Vitoria, Álava, SpainAllergy Section, University General Hospital of Alicante, Calle Pintor Baeza s/n, 03010 Alicante, SpainDepartment of Immunology, Microbiology and Parasitology, Faculty of Pharmacy, Laboratory of Parasitology and Immunoallergy, Center for Research Laskaray, University of the Basque Country, Paseo Universidad, 6, 01006 Vitoria, Álava, SpainAllergy Section, University General Hospital of Alicante, Calle Pintor Baeza s/n, 03010 Alicante, SpainAllergy Section, University General Hospital of Alicante, Calle Pintor Baeza s/n, 03010 Alicante, SpainAllergy Section, University General Hospital of Alicante, Calle Pintor Baeza s/n, 03010 Alicante, SpainDepartment of Immunology, Microbiology and Parasitology, Faculty of Pharmacy, Laboratory of Parasitology and Immunoallergy, Center for Research Laskaray, University of the Basque Country, Paseo Universidad, 6, 01006 Vitoria, Álava, SpainWe report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bisporus mushroom were identified as patient-specific IgE-binding proteins. Cross-reactivity between A. bisporus MnSOD and mold aeroallergens was confirmed. We conclude that prior sensitization to mold aeroallergens might explain severe food reactions to cross-reacting homologs mushroom proteins.http://www.sciencedirect.com/science/article/pii/S2211753915000081Agaricus bisporusAnaphylaxisCross-reactivityFood allergyMold allergy
collection DOAJ
language English
format Article
sources DOAJ
author Marta F. Gabriel
Purificación González-Delgado
Idoia Postigo
Javier Fernández
Victor Soriano
Begoña Cueva
Jorge Martínez
spellingShingle Marta F. Gabriel
Purificación González-Delgado
Idoia Postigo
Javier Fernández
Victor Soriano
Begoña Cueva
Jorge Martínez
From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
Medical Mycology Case Reports
Agaricus bisporus
Anaphylaxis
Cross-reactivity
Food allergy
Mold allergy
author_facet Marta F. Gabriel
Purificación González-Delgado
Idoia Postigo
Javier Fernández
Victor Soriano
Begoña Cueva
Jorge Martínez
author_sort Marta F. Gabriel
title From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_short From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_full From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_fullStr From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_full_unstemmed From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_sort from respiratory sensitization to food allergy: anaphylactic reaction after ingestion of mushrooms (agaricus bisporus)
publisher Elsevier
series Medical Mycology Case Reports
issn 2211-7539
publishDate 2015-06-01
description We report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bisporus mushroom were identified as patient-specific IgE-binding proteins. Cross-reactivity between A. bisporus MnSOD and mold aeroallergens was confirmed. We conclude that prior sensitization to mold aeroallergens might explain severe food reactions to cross-reacting homologs mushroom proteins.
topic Agaricus bisporus
Anaphylaxis
Cross-reactivity
Food allergy
Mold allergy
url http://www.sciencedirect.com/science/article/pii/S2211753915000081
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