Synthesis, Structure and Antitumor Activity of Dibutyltin Oxide Complexes with 5-Fluorouracil Derivatives. Crystal Structure of [(5-Fluorouracil)-1-CH2CH2COOSn(n-Bu) 2]4O2

Synthesis, Structure and Antitumor Activity of Dibutyltin Oxide Complexes with 5-Fluorouracil Derivatives. Crystal Structure of [(5-Fluorouracil)-1-CH2CH2COOSn(n-Bu) 2]4O2

Dibutyltin (IV) oxide complex reacts with the fluorouracil compounds 5-fluorouracil-1-propanonic or 5-fluorouracil-1-acetic acid (Fu) to give the complexes [(5-Fu)-1-(CH2)nCOOSn(n-Bu)2]4O2 (I, n=2; II, n=1) which were characterized by IR and 1H-NMR. The crystal structure of complex I shows that the...

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Bibliographic Details
Main Authors: Zhan Shi, Xin Qi, Kui-qi Wang, Hua-shi Guan, Tao Jiang, Dai-shu Zuo
Format: Article
Language:English
Published: MDPI AG 2001-07-01
Series:Molecules
Subjects:
Organotin complex
5-Fu
synthesis
crystal structure
antitumor activity
Online Access:http://www.mdpi.com/1420-3049/6/8/647/

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