Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling

Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling

Increasing evidences indicate that reactive oxygen species are the main factor promoting stem cell aging. Recent studies have demonstrated that coenzyme Q10 (CoQ10) plays a positive role in organ and cellular aging. However, the potential for CoQ10 to protect stem cell aging has not been fully evalu...

Full description

Bibliographic Details
Main Authors:	Dayong Zhang, Bingxi Yan, Shanshan Yu, Chong Zhang, Baoming Wang, Yayan Wang, Junbo Wang, Zhanggen Yuan, Lihuang Zhang, Jianping Pan
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2015/867293

Similar Items

Coenzyme Q10 Ameliorates Pancreatic Fibrosis via the ROS-Triggered mTOR Signaling Pathway
by: Ran Xue, et al.
Published: (2019-01-01)

The paradox of Akt -mTOR interactions
by: LAKSHMIPATHI eVADLAKONDA, et al.
Published: (2013-06-01)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
by: Kerstin Tiedemann, et al.
Published: (2017-05-01)

Mitochondrial Coenzyme Q Protects Sepsis-Induced Acute Lung Injury by Activating PI3K/Akt/GSK-3β/mTOR Pathway in Rats
by: Ruirui Li, et al.
Published: (2019-01-01)

Akt and mTOR in B cell activation and differentiation
by: David A. Fruman, et al.
Published: (2012-08-01)

YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
by: Wei Xu, et al.
Published: (2021-01-01)

SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway
by: Xu H, et al.
Published: (2018-07-01)

Involvement of Akt/mTOR in the Neurotoxicity of Rotenone-Induced Parkinson’s Disease Models
by: Yu Zhang, et al.
Published: (2019-10-01)

Akt1 enhances CA916798 expression through mTOR pathway.
by: Yu-Liang Wang, et al.
Published: (2013-01-01)

Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells
by: Yao Shi, et al.
Published: (2020-01-01)

Zearalenone Induces Apoptosis and Cytoprotective Autophagy in Chicken Granulosa Cells by PI3K-AKT-mTOR and MAPK Signaling Pathways
by: Yifeng Zhu, et al.
Published: (2021-03-01)

PI3K/AKT/mTOR pathway in Angiogenesis
by: Jayashree eKarar, et al.
Published: (2011-12-01)

Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade
by: Yan Chen Shang, et al.
Published: (2012-10-01)

Research Progress on PI3K/AKT/mTOR Signaling Pathway in Burkitt Lymphoma
by: SUN Yuanyuan, et al.
Published: (2019-02-01)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways
by: Wen Wen, et al.
Published: (2020-09-01)

Procyanidin B2 induces apoptosis and autophagy in gastric cancer cells by inhibiting Akt/mTOR signaling pathway
by: Yuqin Li, et al.
Published: (2021-02-01)

Activation of Akt/mTOR pathway is associated with poor prognosis of nasopharyngeal carcinoma.
by: Weiyuan Wang, et al.
Published: (2014-01-01)

The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas
by: Juan Du, et al.
Published: (2016-01-01)

Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway
by: Ling Li, et al.
Published: (2019-02-01)

Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway
by: Lungang Shi, et al.
Published: (2019-07-01)

Stigmasterol Simultaneously Induces Apoptosis and Protective Autophagy by Inhibiting Akt/mTOR Pathway in Gastric Cancer Cells
by: Huange Zhao, et al.
Published: (2021-02-01)

Carcinoma da bexiga: via de sinalização PI3K/Akt/mTOR e inibidores do mTOR
by: Maria do Céu dos Santos Silva Costa
Published: (2019)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
by: Tian Tian, et al.
Published: (2019-02-01)

PI3K/Akt/mTOR inhibitors in breast cancer
by: Joycelyn JX Lee, et al.
Published: (2015-12-01)

Targeting PI3K/Akt/mTOR Signaling In Cancer
by: Camillo ePorta, et al.
Published: (2014-04-01)

Advanced Research of mTOR and Lung Carcinoid Tumors
by: Zixuan ZHANG, et al.
Published: (2013-01-01)

Hepatitis B virus X gene inhibits hepatocyte apoptosis in mice via Akt/mTOR pathway
by: WANG Xue, et al.
Published: (2019-05-01)

Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity
by: Zhang H, et al.
Published: (2019-05-01)

The PI3K/AKT/mTOR signaling pathway is overactivated in primary aldosteronism.
by: Hengchuan Su, et al.
Published: (2013-01-01)

FGFR1 Induces Acquired Resistance Against Gefitinib By Activating AKT/mTOR Pathway In NSCLC
by: Zhang D, et al.
Published: (2019-11-01)

Targeting mTOR for cancer therapy
by: Hui Hua, et al.
Published: (2019-07-01)

Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling
by: Jing Xu, et al.
Published: (2019-11-01)

TTK regulates proliferation and apoptosis of gastric cancer cells through the Akt‐mTOR pathway
by: Hongxia Huang, et al.
Published: (2020-08-01)

Oleic Acid Protects against Hepatic Ischemia and Reperfusion Injury in Mice by Inhibiting AKT/mTOR Pathways
by: Jianrong Guo, et al.
Published: (2019-01-01)

Paeoniflorin attenuates gestational diabetes via Akt/mTOR pathway in a rat model
by: Yonghua Zhang, et al.
Published: (2020-10-01)

Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway
by: Hong Qiao, et al.
Published: (2018-06-01)

Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway
by: Jinjing Yang, et al.
Published: (2018-09-01)

CD155 Promotes the Progression of Cervical Cancer Cells Through AKT/mTOR and NF-κB Pathways
by: Lu Liu, et al.
Published: (2021-06-01)

Oncogenic Ras is downregulated by ARHI and induces autophagy by Ras/AKT/mTOR pathway in glioblastoma
by: Chen Zhong, et al.
Published: (2019-05-01)

The effect of ibrutinib on radiosensitivity in pancreatic cancer cells by targeting EGFR/AKT/mTOR signaling pathway
by: Biqin Tan, et al.
Published: (2020-08-01)