High-throughput sequencing of small RNAs and analysis of differentially expressed microRNAs associated with high-fat diet-induced hepatic insulin resistance in mice

High-throughput sequencing of small RNAs and analysis of differentially expressed microRNAs associated with high-fat diet-induced hepatic insulin resistance in mice

Abstract Background Hepatic insulin resistance (IR) plays a crucial role in the development of many metabolic diseases, such as type 2 diabetes. MicroRNAs (miRNAs) are involved in the pathogenesis of IR and related diseases; however, studies of miRNAs in hepatic IR are limited. Method In this study,...

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Bibliographic Details
Main Authors: Xue Zhao, Zhao Chen, Zengyuan Zhou, Yuzheng Li, Yuanyuan Wang, Zihao Zhou, Huimin Lu, Changhao Sun, Xia Chu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Genes & Nutrition
Subjects:
High-throughput sequencing
MiRNAs
Hepatic insulin resistance
Online Access:http://link.springer.com/article/10.1186/s12263-019-0630-1

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