A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans

A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans

Transcription factor Rme1 regulates meiosis and pseudohyphal growth in baker’s yeast, but its role in the meiosis-defective pathogen Candida albicans is unclear. Here, Hernández-Cervantes et al. show that Rme1 activates the expression of genes required for formation of asexual spores in Candida spec...

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Main Authors: Arturo Hernández-Cervantes, Sadri Znaidi, Lasse van Wijlick, Iryna Denega, Virginia Basso, Jeanne Ropars, Natacha Sertour, Derek Sullivan, Gary Moran, Louise Basmaciyan, Fabienne Bon, Frédéric Dalle, Marie-Elisabeth Bougnoux, Teun Boekhout, Ying Yang, Zongwei Li, Sophie Bachellier-Bassi, Christophe d’Enfert
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20010-9
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spelling doaj-3548548e39414be58497c9944b7e08442021-05-11T08:46:14ZengNature Publishing GroupNature Communications2041-17232020-12-0111111610.1038/s41467-020-20010-9A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicansArturo Hernández-Cervantes0Sadri Znaidi1Lasse van Wijlick2Iryna Denega3Virginia Basso4Jeanne Ropars5Natacha Sertour6Derek Sullivan7Gary Moran8Louise Basmaciyan9Fabienne Bon10Frédéric Dalle11Marie-Elisabeth Bougnoux12Teun Boekhout13Ying Yang14Zongwei Li15Sophie Bachellier-Bassi16Christophe d’Enfert17Unité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCDublin Dental University Hospital and School of Dental Science, Trinity College DublinDublin Dental University Hospital and School of Dental Science, Trinity College DublinUMR PAM, Université de Bourgogne Franche-Comté, AgroSup Dijon – Equipe VAIMiSUMR PAM, Université de Bourgogne Franche-Comté, AgroSup Dijon – Equipe VAIMiSUMR PAM, Université de Bourgogne Franche-Comté, AgroSup Dijon – Equipe VAIMiSUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCWesterdijk Fungal Biodiversity InstituteBeijing Institute of Radiation MedicineCenter for Hospital Infection Control, Institute for Disease Control & PreventionUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, USCTranscription factor Rme1 regulates meiosis and pseudohyphal growth in baker’s yeast, but its role in the meiosis-defective pathogen Candida albicans is unclear. Here, Hernández-Cervantes et al. show that Rme1 activates the expression of genes required for formation of asexual spores in Candida species.https://doi.org/10.1038/s41467-020-20010-9
collection DOAJ
language English
format Article
sources DOAJ
author Arturo Hernández-Cervantes
Sadri Znaidi
Lasse van Wijlick
Iryna Denega
Virginia Basso
Jeanne Ropars
Natacha Sertour
Derek Sullivan
Gary Moran
Louise Basmaciyan
Fabienne Bon
Frédéric Dalle
Marie-Elisabeth Bougnoux
Teun Boekhout
Ying Yang
Zongwei Li
Sophie Bachellier-Bassi
Christophe d’Enfert
spellingShingle Arturo Hernández-Cervantes
Sadri Znaidi
Lasse van Wijlick
Iryna Denega
Virginia Basso
Jeanne Ropars
Natacha Sertour
Derek Sullivan
Gary Moran
Louise Basmaciyan
Fabienne Bon
Frédéric Dalle
Marie-Elisabeth Bougnoux
Teun Boekhout
Ying Yang
Zongwei Li
Sophie Bachellier-Bassi
Christophe d’Enfert
A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
Nature Communications
author_facet Arturo Hernández-Cervantes
Sadri Znaidi
Lasse van Wijlick
Iryna Denega
Virginia Basso
Jeanne Ropars
Natacha Sertour
Derek Sullivan
Gary Moran
Louise Basmaciyan
Fabienne Bon
Frédéric Dalle
Marie-Elisabeth Bougnoux
Teun Boekhout
Ying Yang
Zongwei Li
Sophie Bachellier-Bassi
Christophe d’Enfert
author_sort Arturo Hernández-Cervantes
title A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
title_short A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
title_full A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
title_fullStr A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
title_full_unstemmed A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans
title_sort conserved regulator controls asexual sporulation in the fungal pathogen candida albicans
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-12-01
description Transcription factor Rme1 regulates meiosis and pseudohyphal growth in baker’s yeast, but its role in the meiosis-defective pathogen Candida albicans is unclear. Here, Hernández-Cervantes et al. show that Rme1 activates the expression of genes required for formation of asexual spores in Candida species.
url https://doi.org/10.1038/s41467-020-20010-9
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