Inhibition of cancer stem cell like cells by a synthetic retinoid

The discovery of efficient drugs is a main challenge in cancer therapy. Here, the authors report a synthetic retinoid, WYC-209 with anti-tumor and anti-metastatic activity mediated by the retinoic acid receptor signaling pathway.

Bibliographic Details
Main Authors: Junwei Chen, Xin Cao, Quanlin An, Yao Zhang, Ke Li, Wenting Yao, Fuchun Shi, Yanfang Pan, Qiong Jia, Wenwen Zhou, Fang Yang, Fuxiang Wei, Ning Wang, Biao Yu
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03877-7

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