Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement

Aiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available <i>Moringa oleifera</i> dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochl...

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Main Authors:	Karolina Starzak, Bernadette Creaven, Arkadiusz Matwijczuk, Alicja Matwijczuk, Dariusz Karcz
Format:	Article
Language:	English
Published:	MDPI AG 2019-09-01
Series:	Molecules
Subjects:	<i>Moringa oleifera</i> hypochlorite scavenging free radicals antioxidative potential inflammation coumarins DPPH
Online Access:	https://www.mdpi.com/1420-3049/24/18/3330

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spelling	doaj-353eb4d1135b4efdb105dea0516033222020-11-25T02:42:11ZengMDPI AGMolecules1420-30492019-09-012418333010.3390/molecules24183330molecules24183330Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet SupplementKarolina Starzak0Bernadette Creaven1Arkadiusz Matwijczuk2Alicja Matwijczuk3Dariusz Karcz4Department of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, Warszawska 24, 31-155 Cracow, PolandCentre of Applied Science for Health, Technological University Tallaght, Dublin 24, IrelandDepartment of Biophysics, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, PolandDepartment of Biophysics, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, PolandDepartment of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, Warszawska 24, 31-155 Cracow, PolandAiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available <i>Moringa oleifera</i> dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochlorite activity of the extract was assessed using the hypochlorite-specific coumarin-based fluorescence turn-off sensor, namely 7-diethylamino-coumarin-3-carboxylic acid (7-DCCA). This compound was synthesized via the Knoevenagel condensation of 4-diethylamino-2-hydroxybenzaldehyde with Meldrum’s acid and the Moringa extract was employed as a medium and catalyst. Moreover, the total phenolic content (TPC) as well as the reactive oxygen species (ROS)−scavenging ability of the aqueous Moringa extract were determined. The results obtained demonstrated the applicability of Moringa extract as an anti-hypochlorite agent. Additionally, the satisfactory yield of the 7-DCCA obtained suggests the usefulness of the extract as a catalyst and the reaction medium. The antioxidative potential of the extract was notably lower than that of the standard (TROLOX). Determination of TPC in 100 g of the dry weight (DW) of studied material revealed a high number of polyphones present.https://www.mdpi.com/1420-3049/24/18/3330<i>Moringa oleifera</i>hypochloritescavengingfree radicalsantioxidative potentialinflammationcoumarinsDPPH
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Karolina Starzak Bernadette Creaven Arkadiusz Matwijczuk Alicja Matwijczuk Dariusz Karcz
spellingShingle	Karolina Starzak Bernadette Creaven Arkadiusz Matwijczuk Alicja Matwijczuk Dariusz Karcz Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement Molecules <i>Moringa oleifera</i> hypochlorite scavenging free radicals antioxidative potential inflammation coumarins DPPH
author_facet	Karolina Starzak Bernadette Creaven Arkadiusz Matwijczuk Alicja Matwijczuk Dariusz Karcz
author_sort	Karolina Starzak
title	Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement
title_short	Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement
title_full	Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement
title_fullStr	Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement
title_full_unstemmed	Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement
title_sort	anti-hypochlorite and catalytic activity of commercially available <i>moringa oleifera</i> diet supplement
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2019-09-01
description	Aiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available <i>Moringa oleifera</i> dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochlorite activity of the extract was assessed using the hypochlorite-specific coumarin-based fluorescence turn-off sensor, namely 7-diethylamino-coumarin-3-carboxylic acid (7-DCCA). This compound was synthesized via the Knoevenagel condensation of 4-diethylamino-2-hydroxybenzaldehyde with Meldrum’s acid and the Moringa extract was employed as a medium and catalyst. Moreover, the total phenolic content (TPC) as well as the reactive oxygen species (ROS)−scavenging ability of the aqueous Moringa extract were determined. The results obtained demonstrated the applicability of Moringa extract as an anti-hypochlorite agent. Additionally, the satisfactory yield of the 7-DCCA obtained suggests the usefulness of the extract as a catalyst and the reaction medium. The antioxidative potential of the extract was notably lower than that of the standard (TROLOX). Determination of TPC in 100 g of the dry weight (DW) of studied material revealed a high number of polyphones present.
topic	<i>Moringa oleifera</i> hypochlorite scavenging free radicals antioxidative potential inflammation coumarins DPPH
url	https://www.mdpi.com/1420-3049/24/18/3330
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Anti-Hypochlorite and Catalytic Activity of Commercially Available <i>Moringa oleifera</i> Diet Supplement

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