Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

<p>Abstract</p> <p>Background</p> <p>Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) neurons, produces antinociception and analgesia. The spinal mechanism...

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Bibliographic Details
Main Authors: Schlichter Rémy, Freund-Mercier Marie, Vergnano Angela, Uhl-Bronner Sandra, Veinante Pierre, Breton Jean-Didier, Poisbeau Pierrick
Format: Article
Language:English
Published: SAGE Publishing 2008-05-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/4/1/19

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http://www.molecularpain.com/content/4/1/19

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