Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation

Hibernomas, especially located in the mediastinum, are extremely rare benign tumors, which are important to consider in the differential diagnosis of a heterogeneously enhancing mass with areas of fat attenuation on imaging of an often incidentally discovered mass. Other common possibilities in the...

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Main Authors: Maxine Darke, Anil Dasyam, Matthew Then, Kavita Varma, Amir A. Borhani, Rakesh Varma
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2016/2378143
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spelling doaj-3534cea0efbf4626a6524d76d3d706a92020-11-24T23:28:51ZengHindawi LimitedCase Reports in Radiology2090-68622090-68702016-01-01201610.1155/2016/23781432378143Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic CorrelationMaxine Darke0Anil Dasyam1Matthew Then2Kavita Varma3Amir A. Borhani4Rakesh Varma5University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAUniversity of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAUniversity of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAUniversity of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAUniversity of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAUniversity of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USAHibernomas, especially located in the mediastinum, are extremely rare benign tumors, which are important to consider in the differential diagnosis of a heterogeneously enhancing mass with areas of fat attenuation on imaging of an often incidentally discovered mass. Other common possibilities in the differential include malignant tumors, such as liposarcoma, hence histopathology is usually required to confirm the diagnosis. Hibernomas often follow the distribution of sites of persistence of brown fat in adults, and intrathoracic locations are unusual. We present a very rare case of a mediastinal hibernoma in a 53-year-old woman. She presented to the emergency department with severe, progressive right neck and shoulder pain with radiation down her arm and was found to have a right apical posterior mediastinal mass on imaging. Initial radiographs of the shoulder showed a soft tissue mass within the apical right hemithorax. Further imaging with CT revealed a well circumscribed, heterogeneously enhancing mass with areas of fat attenuation. Pathology confirmed the diagnosis of mediastinal hibernoma, and the mass was completely excised. Fourteen months after surgery, the patient had a normal chest radiograph, and thirty-two months after surgery, she remains asymptomatic.http://dx.doi.org/10.1155/2016/2378143
collection DOAJ
language English
format Article
sources DOAJ
author Maxine Darke
Anil Dasyam
Matthew Then
Kavita Varma
Amir A. Borhani
Rakesh Varma
spellingShingle Maxine Darke
Anil Dasyam
Matthew Then
Kavita Varma
Amir A. Borhani
Rakesh Varma
Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
Case Reports in Radiology
author_facet Maxine Darke
Anil Dasyam
Matthew Then
Kavita Varma
Amir A. Borhani
Rakesh Varma
author_sort Maxine Darke
title Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
title_short Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
title_full Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
title_fullStr Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
title_full_unstemmed Mediastinal Hibernoma: A Rare Case with Radiologic-Pathologic Correlation
title_sort mediastinal hibernoma: a rare case with radiologic-pathologic correlation
publisher Hindawi Limited
series Case Reports in Radiology
issn 2090-6862
2090-6870
publishDate 2016-01-01
description Hibernomas, especially located in the mediastinum, are extremely rare benign tumors, which are important to consider in the differential diagnosis of a heterogeneously enhancing mass with areas of fat attenuation on imaging of an often incidentally discovered mass. Other common possibilities in the differential include malignant tumors, such as liposarcoma, hence histopathology is usually required to confirm the diagnosis. Hibernomas often follow the distribution of sites of persistence of brown fat in adults, and intrathoracic locations are unusual. We present a very rare case of a mediastinal hibernoma in a 53-year-old woman. She presented to the emergency department with severe, progressive right neck and shoulder pain with radiation down her arm and was found to have a right apical posterior mediastinal mass on imaging. Initial radiographs of the shoulder showed a soft tissue mass within the apical right hemithorax. Further imaging with CT revealed a well circumscribed, heterogeneously enhancing mass with areas of fat attenuation. Pathology confirmed the diagnosis of mediastinal hibernoma, and the mass was completely excised. Fourteen months after surgery, the patient had a normal chest radiograph, and thirty-two months after surgery, she remains asymptomatic.
url http://dx.doi.org/10.1155/2016/2378143
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